Genicular Artery Embolization (GAE)
Knee arthritis pain relief — without a knee replacement.
Genicular Artery Embolization (GAE) is a minimally invasive, outpatient treatment for chronic knee osteoarthritis pain. It's designed for people who've tried injections, therapy, and medication but aren't ready for — or want to avoid — surgery.
Bone-on-bone pain with every step? Down the stairs sideways, one hand on the rail, dreading the walk from the car. We hear it every day — and it's treatable.
Does this sound like you?
GAE is often a good fit when knee arthritis pain has stopped responding to the usual treatments.
- ✔Knee pain from arthritis for 6 months or longer
- ✔Cortisone or gel injections stopped working — or never really helped
- ✔Physical therapy and medication haven't given lasting relief
- ✔You want to avoid or delay knee replacement surgery
- ✔You're not a surgical candidate due to weight, age, or health
- ✔Pain disrupts your sleep, walking, or daily activities
How GAE relieves knee pain
Arthritis doesn't just wear down cartilage — the ongoing inflammation makes your body grow tiny, abnormal blood vessels in the joint lining, and those vessels feed still more inflammation in a self-worsening cycle. Painful new nerves grow in right alongside them.
During GAE, an interventional radiologist guides a thin catheter to these small "genicular" arteries and releases microscopic particles that gently reduce that abnormal blood flow. It's the only treatment that calms both the inflammation and the pain nerves at their source — without touching the bone or joint itself.

What to expect
From your first call to lasting relief — most of it happens in a single afternoon.
Consultation & coverage check
We review your history and imaging, confirm you're a candidate, and verify your insurance benefits up front — no surprises.
Procedure day (about 30 minutes)
You're awake but relaxed with light sedation. Through a tiny pinhole in the foot — no cutting — the physician treats the genicular arteries. No general anesthesia.
Home about an hour later
After a short recovery — about an hour after your procedure — you head home. Most people are back to normal activity the very next day.
Relief builds over weeks
Many patients notice pain easing over the following 2–4 weeks as inflammation settles. Results vary from person to person.
GAE vs. your other options
Injections wear off. Surgery is a major operation. GAE targets the source with minimal downside.
| Option | Invasiveness | Typical relief |
|---|---|---|
| Cortisone injection | Low | Only weeks — then it fades |
| Gel (hyaluronic) | Low | Hit-or-miss, temporary |
| GAE (embolization) ★ | Minimal · pinhole | ~70% get lasting relief; no cutting, no implant |
| Knee replacement | Major surgery | Cuts out bone · general anesthesia · months of painful rehab · implant can wear out |
General education, not medical advice. GAE is often the smart step to try before committing to an irreversible operation — your physician will help you decide.
Common questions
Is GAE painful?
How long until I feel better?
Will it "cure" my arthritis?
Can I still have a knee replacement later?
Is it covered by insurance?
Ready to see if GAE is right for your knee?
Take the 2-minute candidacy quiz or check your coverage. Private, no obligation.
See if I'm a candidate